How does a cell in the brain mount a different response to brain cancer than to Alzheimer’s disease? What is the role of context and can we program it for therapeutic benefit? 

Our body is made of over 37 trillion cells. All cells share the same genetic code, yet they are functionally diverse because of the variable states a cell may adopt at scales (intrinsic, micro, macro, environmental) of contexts across time and space. We are at a unique time with access to high-throughput technologies and multimodal datasets at the resolution of individual cells, which allows us to study context-specificity of cell states using approaches that were not possible before.  

Our approach is at the interface of high-throughput multimodal datasets; the design and application of machine-learning and statistical methods, and experiments to get to the “how?.”  We use immune cells as foundational systems as they have a pivotal role in tissue organization, homeostasis and repair across development and disease.

We are an interdisciplinary group of scientists working at the interface of systems biology and precision medicine. Check out the PI’s bio and the CELLestials behind the science. We are recruiting at all levels. Join us!